Haematology
WHO 2016 Polycythemia Vera Criteria calculator
Enter the published formula inputs below to calculate and interpret this score.
Clinical inputs
Allowed range: 8–24 g/dL
Allowed range: 20–75 %
Result
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Clinical inputs
- Sex
- Hemoglobin (g/dL)Accepted range: 8 to 24
- Hematocrit (%)Accepted range: 20 to 75
- Increased red-cell mass
- Bone-marrow hypercellularity with panmyelosis
- JAK2 mutation
- Subnormal serum erythropoietin
Primary source
Arber DA et al. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood. DOI: 10.1182/blood-2016-03-643544. PMID: 27069254. Polycythemia vera requires all 3 major criteria, or the first 2 major criteria plus the minor criterion of a subnormal erythropoietin level. Major criterion 1 is hemoglobin >16.5 g/dL in men or >16.0 g/dL in women, hematocrit >49% in men or >48% in women, or increased red-cell mass. (2016)
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