Haematology · Oncology
Mantle Cell Lymphoma International Prognostic Index (MIPI) calculator
Enter the published formula inputs below to calculate and interpret this score.
Clinical inputs
Allowed range: 18–100 years
Allowed range: 0–4 points
The coefficient 0.6978 is added only when ECOG is greater than 1. ECOG 0 and ECOG 1 do not add it.
Allowed range: 50–5000 U/L
Allowed range: 50–500 U/L
Allowed range: 500–500000 /µL
Enter ×10^9/L. The erratum requires the logarithm of the count per microliter, which is this number times 1000.
Result
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Clinical inputs
- Age (years)Accepted range: 18 to 100
- ECOG performance status (points)Accepted range: 0 to 4
- Lactate dehydrogenase (U/L)Accepted range: 50 to 5000
- Upper reference limit for lactate dehydrogenase (U/L)Accepted range: 50 to 500
- White blood cell count (×10^9/L)Accepted range: 0.5 to 500
Primary source
Hoster E et al. A new prognostic index (MIPI) for patients with advanced-stage mantle cell lymphoma. Blood. DOI: 10.1182/blood-2007-06-095331. PMID: 17962512. Erratum DOI: 10.1182/blood-2008-08-175950. MIPI = 0.03535 × age in years + 0.6978 if ECOG is greater than 1 + 1.367 × log10(LDH/ULN) + 0.9393 × log10(white cells per microliter). Low risk is a score below 5.70 (5-year overall survival 60%), intermediate is 5.70 to below 6.20 (median 51 months), and high is 6.20 or higher (median 29 months). (2008)
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