Haematology · Oncology
NCCN International Prognostic Index calculator
Enter the published formula inputs below to calculate and interpret this score.
Clinical inputs
Allowed range: 18–110 years
Table 3: older than 40 through 60 scores 1, older than 60 through 75 scores 2, and older than 75 scores 3. Age 40 scores 0. Age 60 scores 1. Age 75 scores 2.
Allowed range: 50–8000 U/L
Allowed range: 50–500 U/L
Table 3: a ratio above 1 through 3 scores 1, and a ratio above 3 scores 2. A ratio of exactly 1 scores 0. A ratio of exactly 3 scores 1.
Result
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Clinical inputs
- Age (years)Accepted range: 18 to 110
- Lactate dehydrogenase (U/L)Accepted range: 50 to 8000
- Upper reference limit for lactate dehydrogenase (U/L)Accepted range: 50 to 500
- Ann Arbor stage III or IV
- Disease in bone marrow, central nervous system, liver or gastrointestinal tract, or lung
- ECOG performance status of 2 or higher
Primary source
Zhou Z et al. An enhanced International Prognostic Index (NCCN-IPI) for patients with diffuse large B-cell lymphoma treated in the rituximab era. Blood. DOI: 10.1182/blood-2013-09-524108. PMID: 24264230. Table 3: age >40 to ≤60 = 1, >60 to ≤75 = 2, >75 = 3; LDH ratio >1 to ≤3 = 1, >3 = 2; Ann Arbor III–IV = 1; disease in bone marrow, CNS, liver/GI tract, or lung = 1; ECOG ≥2 = 1. Five-year overall survival in the NCCN cohort was 96% (0–1), 82% (2–3), 64% (4–5), and 33% (≥6). (2014)
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