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Haematology

IPS-E for Early-stage CLL calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

×10^9/L

Allowed range: 0–500 ×10^9/L

Quick picks

One point only when the count is higher than 15 ×10^9/L. A count of exactly 15 does not score.

Result

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Clinical inputs

  • Unmutated IGHV
  • Absolute lymphocyte count (×10^9/L)Accepted range: 0 to 500
  • Palpable lymph nodes

Primary source

Condoluci A et al. International prognostic score for asymptomatic early-stage chronic lymphocytic leukemia. Blood. DOI: 10.1182/blood.2019003453. PMID: 32267500. One point each for unmutated IGHV, absolute lymphocyte count higher than 15 ×10^9/L, and palpable lymph nodes. Score 0 is low risk (5-year treatment risk 8.4%), score 1 is intermediate (28.4%), and scores 2–3 are high (61.2%). (2020)

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