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Haematology · Nephrology

Therapeutic Plasmapheresis Volume calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

lb
Quick picks
%

Enter hematocrit as a fraction, as in the equation 1 minus hematocrit. 40% is 0.40.

Plasma volumes to exchange

Result

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Clinical inputs

  • Weight (kg)
  • Hematocrit (fraction)
  • Plasma volumes to exchange

Primary source

Ahmed S, Kaplan A. Therapeutic Plasma Exchange Using Membrane Plasma Separation. Clin J Am Soc Nephrol. DOI: 10.2215/CJN.12501019. PMID: 32312791. Estimated plasma volume in liters is 0.065 times weight in kilograms times (1 minus hematocrit as a fraction). The usual exchange prescription is 1 to 1.5 times that volume. One plasma volume is described as lowering pretreatment immunoglobulin by about 63%, and 1.4 plasma volumes by about 75%. (2020)

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