Haematology · Oncology

Peripheral Blood Stem Cell Collection calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

Recipient body weight

Allowed range: 2.2–551.16 lb

The formula divides by the recipient's weight, not the donor's.

Donor peripheral blood CD34+ count before collection

cells/µL

Allowed range: 0–2000 cells/µL

Pre-apheresis CD34+ cells per microlitre of donor blood.

Total blood volume processed

Allowed range: 1–40 L

Litres processed in the apheresis session. The published formula uses a fixed collection efficiency of 0.43.

Result

3 fields remaining

Anyone can run this calculator. Sign in to save, favourite, or send the result.

Primary source

de Almeida-Neto C, Rocha V, Moreira FR, Hamasaki DT, Farias MC, Arrifano AM, Witkin SS, Mendrone-Junior A. Validation of a formula predictive of peripheral blood stem cell yield and successful collection in healthy allogeneic donors. Hematol Transfus Cell Ther. 2020;42(2). DOI: 10.1016/j.htct.2019.04.004. PMID: 31439517. Abstract formula: total CD34+ yield (cells x10^6/kg) = [(peripheral CD34+ cells/µL) x (0.43) / recipient body weight (kg)] x total litres processed, where 0.43 is the study's median collection efficiency coefficient (the introduction notes it varies from 30% to 50% by leukapheresis processor; the published formula fixes it at 0.43 and so does this tool). A successful collection was defined as at least 4 x10^6 CD34+ cells/kg in one apheresis session. Predicted and observed yields correlated with r = 0.775 in 338 collections from 307 donors. (2020)

Scope: Healthy mobilised allogeneic donors before leukapheresis; it estimates the CD34+ dose per kg of recipient weight and does not predict mobilisation failure or replace the post-collection product count.

Last reviewed 2026-10-18

View source

Professional use only

For qualified clinicians. Independently verify inputs, calculations, source guidance, and applicability before any clinical action. This calculator does not replace clinical judgment.

Source: de Almeida-Neto C, Rocha V, Moreira FR, Hamasaki DT, Farias MC, Arrifano AM, Witkin SS, Mendrone-Junior A. Validation of a formula predictive of peripheral blood stem cell yield and successful collection in healthy allogeneic donors. Hematol Transfus Cell Ther. 2020;42(2). DOI: 10.1016/j.htct.2019.04.004. PMID: 31439517. Abstract formula: total CD34+ yield (cells x10^6/kg) = [(peripheral CD34+ cells/µL) x (0.43) / recipient body weight (kg)] x total litres processed, where 0.43 is the study's median collection efficiency coefficient (the introduction notes it varies from 30% to 50% by leukapheresis processor; the published formula fixes it at 0.43 and so does this tool). A successful collection was defined as at least 4 x10^6 CD34+ cells/kg in one apheresis session. Predicted and observed yields correlated with r = 0.775 in 338 collections from 307 donors. (2020)

Ruqelo is AI and can make mistakes. Check important information.

Clinical inputs

Recipient body weight (kg)Accepted range: 1 to 250
Donor peripheral blood CD34+ count before collection (cells/µL)Accepted range: 0 to 2000
Total blood volume processedAccepted range: 1 to 40

Primary source

View source