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Haematology

PLASMIC Score calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

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0

Low-risk PLASMIC score (0–4)

Band: Low-risk PLASMIC score (0–4)

Interpretation. Low-risk PLASMIC score (0–4)

Suggested management. Low probability of severe ADAMTS13 deficiency by PLASMIC.

PLASMIC Score: 0 — Low-risk PLASMIC score (0–4). Interpretation: Low-risk PLASMIC score (0–4) What to do: Low probability of severe ADAMTS13 deficiency by PLASMIC. Inputs: Platelet count <30 ×10⁹/L (+1): false; Hemolysis: reticulocytes >2.5%, undetectable haptoglobin, or indirect bilirubin >2.0 mg/dL (+1): false; No active cancer or cancer therapy within the last year (+1): false; No solid-organ or stem-cell transplant (+1): false; Mean corpuscular volume <90 fL (+1): false; INR <1.5 (+1): false; Creatinine <2.0 mg/dL (+1): false Source: Bendapudi PK et al. Derivation and external validation of the PLASMIC score for rapid assessment of adults with thrombotic microangiopathies. Lancet Haematol (2017)

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Clinical inputs

  • Platelet count <30 ×10⁹/L (+1)
  • Hemolysis: reticulocytes >2.5%, undetectable haptoglobin, or indirect bilirubin >2.0 mg/dL (+1)
  • No active cancer or cancer therapy within the last year (+1)
  • No solid-organ or stem-cell transplant (+1)
  • Mean corpuscular volume <90 fL (+1)
  • INR <1.5 (+1)
  • Creatinine <2.0 mg/dL (+1)

Primary source

Bendapudi PK et al. Derivation and external validation of the PLASMIC score for rapid assessment of adults with thrombotic microangiopathies. Lancet Haematol (2017)

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