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Haematology · ICU and Critical Care

Sickle Cell RBC Exchange Volume calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

lb
Quick picks

The 70 mL/kg blood volume is for a child past infancy who is not obese.

fraction

Enter hematocrit as a percent. The printed example uses 25%.

Result

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Clinical inputs

  • Weight (kg)
  • Hematocrit (%)

Primary source

Kelly S. Logistics, risks, and benefits of automated red blood cell exchange for patients with sickle cell disease. Hematology Am Soc Hematol Educ Program. DOI: 10.1182/hematology.2023000498. PMID: 38066846. When device software is not available, the red-cell volume to exchange is 1.5 times the patient's red-cell volume. For children who are not neonates or infants and who are not obese, blood volume is 70 mL/kg and red-cell volume is that blood volume times the hematocrit. The printed example is a 30 kg child with hematocrit 25%: blood volume 2100 mL, red-cell volume 525 mL, and 1.5 times that volume 787.5 mL. (2023)

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