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Neurology

Migraine Treatment Optimization Questionnaire-4 calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

Pain freedom within 2 hours

Never and rarely score 0. Less than half the time scores 1. Half the time or more scores 2.

One dose still helping at 24 hours

Never and rarely score 0. Less than half the time scores 1. Half the time or more scores 2.

Comfortable planning the day

Never and rarely score 0. Less than half the time scores 1. Half the time or more scores 2.

Able to return to usual function

Never and rarely score 0. Less than half the time scores 1. Half the time or more scores 2.

Result

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Clinical inputs

  • Pain freedom within 2 hours
  • One dose still helping at 24 hours
  • Comfortable planning the day
  • Able to return to usual function

Primary source

Lipton RB, Fanning KM, Serrano D, Reed ML, Cady R, Buse DC. Ineffective acute treatment of episodic migraine is associated with new-onset chronic migraine. Neurology. DOI: 10.1212/WNL.0000000000001256. PMID: 25609757. Methods and Table 2: never scores 0, rarely scores 0, less than half the time scores 1, and half the time or more scores 2. The four summed concepts are pain freedom within 2 hours for most attacks, relief from one dose lasting at least 24 hours, enough comfort with the medicine to plan daily activities, and enough control to return to usual function. Very poor efficacy is 0, poor efficacy is 1 to 5, moderate efficacy is 6 to 7, and maximum efficacy is 8. (2015)

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