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Hepatology · Infectious Disease · Gastroenterology

AST to Platelet Ratio Index (APRI) calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

IU/L

Allowed range: 1–2000 IU/L

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IU/L

Allowed range: 1–100 IU/L

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Use your laboratory’s ULN (Wai derivation used 45 IU/L; many labs use ~40)

×10⁹/L

Allowed range: 1–1000 ×10⁹/L

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Result

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Clinical inputs

  • AST (IU/L)Accepted range: 1 to 2000
  • AST upper limit of normal (IU/L)Accepted range: 1 to 100
  • Platelet count (×10⁹/L)Accepted range: 1 to 1000

Primary source

Wai CT et al. A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C. Hepatology. DOI: 10.1053/jhep.2003.50346. PMID: 12883497. Scope: APRI = [(AST/ULN)/platelet count ×10⁹/L] × 100; fibrosis cutoffs ≈0.5 and 1.5; cirrhosis cutoffs ≈1.0 and 2.0. (2003)

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