Hepatology · Gastroenterology

Revised Natural History Model for Primary Sclerosing Cholangitis calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

Age

years

Allowed range: 0–100 years

Total bilirubin

mg/dL

Allowed range: 0.1–50 mg/dL

Aspartate aminotransferase

U/L

Allowed range: 1–5000 U/L

History of variceal bleeding

Serum albumin

g/dL

Allowed range: 0.5–6 g/dL

Result

4 fields remaining

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Clinical inputs

Age (years)Accepted range: 0 to 100
Total bilirubin (mg/dL)Accepted range: 0.1 to 50
Aspartate aminotransferase (U/L)Accepted range: 1 to 5000
History of variceal bleeding
Serum albumin (g/dL)Accepted range: 0.5 to 6

Primary source

Kim WR, Therneau TM, Wiesner RH, et al. A revised natural history model for primary sclerosing cholangitis. Mayo Clin Proc. DOI: 10.4065/75.7.688. PMID: 10907383. Risk score R = 0.03 × age in years + 0.54 × ln(bilirubin in mg/dL) + 0.54 × ln(aspartate aminotransferase in U/L) + 1.24 if variceal bleeding has occurred, otherwise 0, − 0.84 × albumin in g/dL. (2000)

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