Cardiology · Emergency Medicine
Troponin-only Manchester Acute Coronary Syndromes calculator
Enter the published formula inputs below to calculate and interpret this score.
Clinical inputs
Allowed range: 40–260 mmHg
Systolic pressure under 100 mmHg adds its coefficient. A value of 100 does not.
Allowed range: 0–10 ng/mL
Enter nanograms per litre. Nanograms per millilitre convert by multiplying by 1000. The coefficient is 0.089 per ng/L.
Result
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Clinical inputs
- Acute ischaemic changes on the ECG
- Worsening or crescendo angina
- Pain radiating to the right arm or shoulder
- Vomiting
- Sweating observed
- Systolic blood pressure (mmHg)Accepted range: 40 to 260
- Arrival high-sensitivity cardiac troponin T (ng/L)Accepted range: 0 to 10000
Primary source
Body R et al. Troponin-only Manchester Acute Coronary Syndromes (T-MACS) decision aid: single biomarker re-derivation and external validation in three cohorts. Emerg Med J. DOI: 10.1136/emermed-2016-205983. PMID: 27565197. The printed equation is p = 1 / (1 + e^−(1.713E + 0.847A + 0.607R + 1.417V + 2.058S + 1.208H + 0.089T − 4.766)), with E ECG ischaemia, A worsening or crescendo angina, R pain to the right arm or shoulder, V vomiting, S sweating observed, H systolic pressure under 100 mmHg, and T arrival high-sensitivity cardiac troponin T in ng/L. Methods: very low risk is p<0.02, low risk is 0.02<p<0.05, moderate risk is 0.05<p<0.95, and high risk is p≥0.95. The group follows that unrounded probability. The paper leaves p exactly 0.02 and p exactly 0.05 outside every group. (2017)
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