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Gastroenterology

Rome IV Functional Heartburn calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

months

Allowed range: 0–240 months

Quick picks

The source requires symptoms over the last 3 months and onset at least 6 months earlier.

months

Allowed range: 0–24 months

Quick picks

The source requires symptoms over the last 3 months and onset at least 6 months earlier.

days/week

Allowed range: 0–7 days/week

Quick picks

Result

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Clinical inputs

  • Months since symptom onsetAccepted range: 0 to 240
  • Months the criteria have been fulfilledAccepted range: 0 to 24
  • Days per week with the symptom (days/week)Accepted range: 0 to 7
  • No major esophageal motor disorder
  • Burning retrosternal discomfort or pain
  • No relief despite optimal antisecretory therapy
  • Acid exposure time is above the reference range
  • Symptom-reflux association is positive
  • Eosinophilic esophagitis is absent

Primary source

Aziz Q, Fass R, Gyawali CP, Miwa H, Pandolfino JE, Zerbib F. Functional esophageal disorders. Gastroenterology. DOI: 10.1053/j.gastro.2016.02.012. PMID: 27144625. Functional heartburn requires burning retrosternal discomfort or pain, no relief despite optimal antisecretory therapy, no eosinophilic esophagitis, and no major esophageal motor disorder. Reflux evidence is elevated acid exposure, a positive symptom-reflux association, or both; either finding alone keeps the result at 0. Neither finding, together with no eosinophilic esophagitis, can meet the criterion. Criteria are fulfilled for the past 3 months, with onset at least 6 months earlier, at least twice a week. (2016)

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