Emergency Medicine · Toxicology · ICU and Critical Care

High-Dose Insulin Starting Infusion calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

Body weight

Allowed range: 66.14–551.16 lb

The consensus uses 1 unit/kg. It does not print a kilogram cap. The 30 kg and 250 kg entry limits are not printed caps.

Result

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Primary source

St-Onge M et al. Experts Consensus Recommendations for the Management of Calcium Channel Blocker Poisoning in Adults. Crit Care Med. PMID: 27749343. The proposed regimen of regular insulin is a bolus of 1 unit/kg followed by an infusion of 1 unit/kg/h, with euglycemia maintained by a dextrose infusion as needed. Titration up to 10 units/kg/h is the printed upper rate for patients who do not respond to first-line therapies or who have refractory shock. The result is the 1 unit/kg/h infusion in units/h. The bolus and the 10 units/kg/h ceiling are separate lines. The paper does not print a kilogram cap or a fixed dextrose rate, so neither was added. The 30 kg and 250 kg entry limits are not printed caps. The dose has to be verified against the local protocol. (2017)

Scope: Adults with calcium channel blocker poisoning when high-dose insulin is dosed from the 2017 consensus regimen.

Last reviewed 2026-10-17

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Professional use only

For qualified clinicians. Independently verify inputs, calculations, source guidance, and applicability before any clinical action. This calculator does not replace clinical judgment.

Source: St-Onge M et al. Experts Consensus Recommendations for the Management of Calcium Channel Blocker Poisoning in Adults. Crit Care Med. PMID: 27749343. The proposed regimen of regular insulin is a bolus of 1 unit/kg followed by an infusion of 1 unit/kg/h, with euglycemia maintained by a dextrose infusion as needed. Titration up to 10 units/kg/h is the printed upper rate for patients who do not respond to first-line therapies or who have refractory shock. The result is the 1 unit/kg/h infusion in units/h. The bolus and the 10 units/kg/h ceiling are separate lines. The paper does not print a kilogram cap or a fixed dextrose rate, so neither was added. The 30 kg and 250 kg entry limits are not printed caps. The dose has to be verified against the local protocol. (2017)

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Clinical inputs

Body weight (kg)Accepted range: 30 to 250

Primary source

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