Cardiology
Grogan Staging for Wild-type ATTR Cardiomyopathy calculator
Enter the published formula inputs below to calculate and interpret this score.
Clinical inputs
Allowed range: 0–10 ng/mL
Stage assignment uses a cutoff of 0.05 ng/mL. A value equal to 0.05 is not above the cutoff.
Allowed range: 10–100000 pg/mL
Stage assignment uses a cutoff of 3000 pg/mL. A value equal to 3000 is not above the cutoff. pg/mL and ng/L are the same number.
Result
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Clinical inputs
- Troponin T (ng/mL)Accepted range: 0 to 10
- NT-proBNP (pg/mL)Accepted range: 10 to 100000
Primary source
Grogan M et al. Natural history of wild-type transthyretin cardiac amyloidosis and risk stratification using a novel staging system. J Am Coll Cardiol. DOI: 10.1016/j.jacc.2016.06.033. PMID: 27585505. Stage I is troponin T and NT-proBNP both at or below 0.05 ng/mL and 3000 pg/mL. Stage II is exactly one marker above its cutoff. Stage III is both above. Four-year overall survival was 57%, 42%, and 18%. Median survival in stage III was 20 months. (2016)
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