Infectious Disease · Nephrology
D:A:D HIV CKD risk score calculator
Enter the published formula inputs below to calculate and interpret this score.
Clinical inputs
Allowed range: 16–100 years
Years. 35 or younger scores 0, older than 35 through 50 scores 4, older than 50 through 60 scores 7, and older than 60 scores 10.
Allowed range: 1–250 mL/min/1.73 m²
Cockcroft-Gault value standardized to body surface area, in mL/min/1.73 m². Above 60 through 70 scores 6, above 70 through 90 scores 0, and above 90 scores −6. A value of 60 or below is not scored.
Allowed range: 0–5000 cells/mm³
Cells per mm³. A nadir above 200 scores −1. A nadir of 200 or below scores 0.
Result
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Clinical inputs
- Age (years)Accepted range: 16 to 100
- Sex
- Baseline eGFR (mL/min/1.73 m²)Accepted range: 1 to 250
- Nadir CD4 count (cells/mm³)Accepted range: 0 to 5000
- Injection drug use as the HIV exposure
- Hepatitis C coinfection
- Hypertension
- Prior cardiovascular disease
- Diabetes mellitus
Primary source
Mocroft A et al. Development and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study. PLoS Med. DOI: 10.1371/journal.pmed.1001809. PMID: 25826420. Table 2 full integer score: intravenous drug use 2, hepatitis C 1, age ≤35 is 0, >35 to ≤50 is 4, >50 to ≤60 is 7, >60 is 10, baseline eGFR >60 to ≤70 is 6, >70 to ≤90 is 0, >90 is −6, female 1, nadir CD4 >200 is −1, hypertension 1, prior cardiovascular disease 1, diabetes 2. Low is a score below 0, medium is 0–4, and high is 5 or more. An eGFR of 60 or below has no row. (2015)
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