Infectious Disease
VACS Index 1.0 calculator
Enter the published formula inputs below to calculate and interpret this score.
Clinical inputs
Allowed range: 18–100 years
Under 50 scores 0, 50 through 64 scores 12, and older than 65 scores 27. Age 65 has no row.
Allowed range: 0–5000 cells/µL
Cells per microliter. Above 500 scores 0. Exactly 500 has no row. Below 50 scores 29.
Allowed range: 0–10000000 copies/mL
Copies per mL. Under 500 scores 0, 500 through 100000 inclusive scores 7, and above 100000 scores 14.
Allowed range: 2–22 g/dL
Grams per deciliter. Above 14 scores 0, 12 to 13.9 scores 10, 10 to 11.9 scores 22, and below 10 scores 38. Exactly 14, and the gap above 11.9 and below 12, have no row.
Allowed range: 1–5000 U/L
Allowed range: 1–5000 U/L
Allowed range: 1–2000 ×10⁹/L
Enter the count as ×10⁹/L, so 150 means 150. FIB-4 divides age times AST by platelets times the square root of ALT.
Allowed range: 0.1–20 mg/dL
Milligrams per deciliter in the printed filtration equation: 186.3 × creatinine to the power −1.154 × age to the power −0.203.
Result
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Clinical inputs
- Age in yearsAccepted range: 18 to 100
- Sex, for the filtration equation
- Black, for the filtration coefficient
- CD4 cell count (cells/µL)Accepted range: 0 to 5000
- HIV-1 RNA (copies/mL)Accepted range: 0 to 10000000
- Hemoglobin (g/dL)Accepted range: 2 to 22
- Aspartate aminotransferase (U/L)Accepted range: 1 to 5000
- Alanine aminotransferase (U/L)Accepted range: 1 to 5000
- Platelet count (×10⁹/L)Accepted range: 1 to 2000
- Serum creatinine (mg/dL)Accepted range: 0.1 to 20
- Hepatitis C infection
Primary source
Tate JP et al. An internationally generalizable risk index for mortality after one year of antiretroviral therapy. AIDS. DOI: 10.1097/QAD.0b013e32835b8c7f. PMID: 23095314. Table 2 VACS Index points: age <50 is 0, 50–64 is 12, >65 is 27; CD4 >500 is 0, 350–499 is 6, 200–349 is 6, 100–199 is 10, 50–99 is 28, <50 is 29; HIV-1 RNA <500 is 0, 500 through 100000 inclusive is 7, >100000 is 14; hemoglobin >14 is 0, 12–13.9 is 10, 10–11.9 is 22, <10 is 38; FIB-4 <1.45 is 0, 1.45–3.25 is 6, >3.25 is 25; eGFR >60 is 0, 45–59.9 is 6, 30–44.9 is 8, <30 is 26; hepatitis C is 5. FIB-4 = (age × AST) / (platelets × square root of ALT). eGFR = 186.3 × creatinine^−1.154 × age^−0.203 × 0.742 if female × 1.21 if Black. Age 65, CD4 500, hemoglobin 14, and eGFR 60 are not given a point row. (2013)
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