Cardiology · Endocrinology · Genetics
Simon Broome Familial Hypercholesterolemia Criteria calculator
Enter the published formula inputs below to calculate and interpret this score.
Clinical inputs
Allowed range: 1–90 years
Allowed range: 77.34–773.4 mg/dL
Allowed range: 19.33–580.05 mg/dL
Result
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Clinical inputs
- Age (years)Accepted range: 1 to 90
- Total cholesterol (mmol/L)Accepted range: 2 to 20
- LDL cholesterol (mmol/L)Accepted range: 0.5 to 15
- Tendon xanthoma in the patient or a first- or second-degree relative
- DNA mutation diagnostic of familial hypercholesterolemia
- Family history of myocardial infarction or of raised cholesterol
Primary source
Scientific Steering Committee on behalf of the Simon Broome Register Group. Risk of fatal coronary heart disease in familial hypercholesterolaemia. BMJ. PMID: 1933004. Definite FH is the cholesterol threshold plus tendon xanthomas in the patient or a first- or second-degree relative, or a DNA mutation. Possible FH is the cholesterol threshold plus a family history of myocardial infarction or of raised cholesterol. Adult thresholds are total cholesterol >7.5 mmol/L or LDL >4.9 mmol/L; child thresholds are >6.7 and >4.0 mmol/L. (1991)
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