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Cardiology · Haematology

SAMe-TT₂R₂ Score for VKA Control calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

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SAMe-TT₂R₂ 0–1 — likely better VKA control

Band: SAMe-TT₂R₂ 0–1 — likely better VKA control

Interpretation. SAMe-TT₂R₂ 0–1 — likely better VKA control

Suggested management. Lower score predicts better time in therapeutic range on VKA.

SAMe-TT₂R₂ Score for VKA Control: 0 — SAMe-TT₂R₂ 0–1 — likely better VKA control. Interpretation: SAMe-TT₂R₂ 0–1 — likely better VKA control What to do: Lower score predicts better time in therapeutic range on VKA. Inputs: Sex female (+1): false; Age <60 years (+1): false; Medical history — more than two comorbidities (+1): false; Treatment with interacting drugs (e.g., amiodarone) (+1): false; Tobacco use (+2): false; Race non-Caucasian (+2): false Source: Apostolakis S et al. Factors affecting quality of anticoagulation control among patients with atrial fibrillation on warfarin: the SAMe-TT₂R₂ score. Chest. DOI: 10.1378/chest.13-0054. PMID: 23669885. Scope: Sex (female)+1, Age <60 +1, Medical history (>2 comorbidities)+1, Treatment (interacting drugs e.g. amiodarone)+1, Tobacco +2, Race (non-Caucasian)+2; 0–1 predicts better TTR on VKA, ≥2 poorer control. (2013)

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Clinical inputs

  • Sex female (+1)
  • Age <60 years (+1)
  • Medical history — more than two comorbidities (+1)
  • Treatment with interacting drugs (e.g., amiodarone) (+1)
  • Tobacco use (+2)
  • Race non-Caucasian (+2)

Primary source

Apostolakis S et al. Factors affecting quality of anticoagulation control among patients with atrial fibrillation on warfarin: the SAMe-TT₂R₂ score. Chest. DOI: 10.1378/chest.13-0054. PMID: 23669885. Scope: Sex (female)+1, Age <60 +1, Medical history (>2 comorbidities)+1, Treatment (interacting drugs e.g. amiodarone)+1, Tobacco +2, Race (non-Caucasian)+2; 0–1 predicts better TTR on VKA, ≥2 poorer control. (2013)

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