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Cardiology · Endocrinology · Genetics · Primary Care

Dutch Lipid Clinic Network Criteria for Familial Hypercholesterolemia calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

Family history
Clinical history
Physical examination
LDL-C (mg/dL)
DNA analysis

Result

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Clinical inputs

  • Family history
  • Clinical history
  • Physical examination
  • LDL-C (mg/dL)
  • DNA analysis

Primary source

Nordestgaard BG et al. Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease. Eur Heart J. DOI: 10.1093/eurheartj/eht273. PMID: 23956253. Scope: endorses Dutch Lipid Clinic Network (WHO) FH criteria — family history 1–2, clinical vascular disease 1–2, xanthomas/corneal arcus 4–6, untreated LDL-C bands 1/3/5/8, pathogenic DNA mutation +8; totals <3 unlikely, 3–5 possible, 6–8 probable, >8 definite FH. (2013)

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