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Cardiology · Haematology · Internal Medicine

DOAC Score for Bleeding Risk calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

Age
Creatinine clearance (CrCl)
Antiplatelet use

Result

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Clinical inputs

  • Age
  • Creatinine clearance (CrCl)
  • Underweight
  • History of stroke
  • Diabetes
  • Hypertension
  • Antiplatelet use
  • NSAID use
  • Liver disease
  • History of bleeding

Primary source

Aggarwal R et al. Development and Validation of the DOAC Score: A Novel Bleeding Risk Prediction Tool for Patients With Atrial Fibrillation on Direct-Acting Oral Anticoagulants. Circulation. DOI: 10.1161/CIRCULATIONAHA.123.065530. PMID: 37621213. Scope: age, kidney function, underweight, prior stroke, diabetes, hypertension, antiplatelet/NSAID use, liver disease, and bleeding history points stratify DOAC bleeding risk. Points (Table 2): age 65–69 = 2, 70–74 = 3, 75–79 = 4, ≥80 = 5; creatinine clearance 30–60 = 1, <30 = 2 mL/min; BMI <18.5 = 1; stroke/TIA/embolism = 1; diabetes = 1; hypertension = 1; aspirin = 2 or dual antiplatelet therapy = 3; NSAID = 1; bleeding history = 3; liver disease = 2. Totals of 10 or more are scored as 10. One-year major bleeding risk groups: 0–3 very low, 4–5 low, 6–7 moderate, 8–9 high, 10 very high. (2023)

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