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Pulmonology · Cardiology

REVEAL 2.0 Risk Score calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

PAH cause
Sex
years

Allowed range: 18–100 years

Quick picks

Men older than 60 years score 2. Men aged 60 and all women score 0 for this item.

Renal insufficiency

eGFR under 60 mL/min/1.73 m2, or renal insufficiency judged clinically when eGFR is unavailable.

Functional class
All-cause hospitalization in the past 6 months
mm Hg

Allowed range: 50–250 mm Hg

Quick picks

Under 110 mm Hg scores 1. A pressure of 110 does not.

beats/min

Allowed range: 30–220 beats/min

Quick picks

Over 96 beats per minute scores 1. A rate of 96 does not.

Six-minute walk distance

Distances are in meters. A walk that was not done scores 0.

BNP or NT-proBNP

Use the row that matches the measured peptide. The interval with no listed points scores 0.

Pericardial effusion
DLCO percent predicted
Mean right atrial pressure
Pulmonary vascular resistance

Result

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Clinical inputs

  • PAH cause
  • Sex
  • Age (years)Accepted range: 18 to 100
  • Renal insufficiency
  • Functional class
  • All-cause hospitalization in the past 6 months
  • Systolic blood pressure (mm Hg)Accepted range: 50 to 250
  • Heart rate (beats/min)Accepted range: 30 to 220
  • Six-minute walk distance
  • BNP or NT-proBNP
  • Pericardial effusion
  • DLCO percent predicted
  • Mean right atrial pressure
  • Pulmonary vascular resistance

Primary source

Benza RL et al. Predicting survival in patients with pulmonary arterial hypertension: the REVEAL risk score calculator 2.0 and comparison with ESC/ERS-based risk assessment strategies. Chest. DOI: 10.1016/j.chest.2019.02.004. PMID: 30772387. The 13-variable point table is printed in Benza RL et al. Chest. DOI: 10.1016/j.chest.2020.08.2069. PMCID: PMC7462639, Table 1. Add 6 to the sum. Connective-tissue disease +1, heritable +2, portopulmonary +3. Men older than 60 years +2. eGFR under 60 mL/min/1.73 m2 +1. Functional class I −1, III +1, IV +2. Hospitalization within 6 months +1. Systolic pressure under 110 mm Hg +1. Heart rate over 96 beats/min +1. Six-minute walk at least 440 m −2, 320 to under 440 m −1, under 165 m +1. BNP under 50 pg/mL or NT-proBNP under 300 pg/mL −2, BNP 200 to under 800 pg/mL +1, BNP at least 800 pg/mL or NT-proBNP at least 1100 pg/mL +2. Pericardial effusion +1. DLCO under 40% predicted +1. Mean right atrial pressure over 20 mm Hg +1. PVR under 5 Wood units −1. A missing item scores 0. Low risk is 0–6, intermediate is 7–8, and high risk is 9 or higher. (2019)

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