Neurology · Clinical Pharmacology

Phenytoin Correction for Albumin calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

Measured total phenytoin

µg/mL

Allowed range: 0.5–40 µg/mL

Serum albumin

g/dL

Allowed range: 1–6 g/dL

End-stage renal disease

Result

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Clinical inputs

Measured total phenytoin (µg/mL)Accepted range: 0.5 to 40
Serum albumin (g/dL)Accepted range: 1 to 6
End-stage renal disease

Primary source

Barra ME, Phillips KM, Chung DY, Rosenthal ES. Prediction Accuracy of Winter-Tozer Equations to Estimate Free Phenytoin Concentrations. Pharmacotherapy. PMID: 29029667, stating the Winter-Tozer equations. With ordinary renal function the normalized concentration is the measured total divided by (0.2 × albumin in g/dL + 0.1). In end-stage renal disease the albumin coefficient is 0.1. The 10–20 µg/mL band is the usual total-phenytoin reference applied to that normalized value. (2017)

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