Neonatology · Paediatrics

Neonatal Partial Exchange for Polycythemia calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

Infant weight

Allowed range: 0.88–13.23 lb

Blood volume per kilogram

mL/kg

Allowed range: 70–110 mL/kg

The guideline gives 70 to 90 mL/kg for term infants and 85 to 110 mL/kg for preterm infants.

Observed venous haematocrit

Allowed range: 60–90 %

The guideline recommends partial exchange for symptomatic infants with a haematocrit above 70%.

Desired haematocrit

Allowed range: 45–60 %

The guideline aims to reduce the venous haematocrit below 60%.

Result

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Primary source

Safer Care Victoria, Clinical Guidance Team (Victoria, Australia). Polycythaemia in neonates. Neonatal eHandbook clinical guidance, first published May 2015, review due May 2018; the page states its review process is paused. Formula: volume of exchange (mL) = blood volume x (observed haematocrit - desired haematocrit) / observed haematocrit. Blood volume is 70-90 mL/kg for term infants and 85-110 mL/kg for preterm infants. The guidance recommends partial exchange transfusion with normal saline as the replacement fluid for symptomatic infants with a venous haematocrit above 70%, aiming to reduce the venous haematocrit below 60%. (2015)

Scope: Neonates with polycythaemia in whom partial exchange is planned. The result is the volume to exchange; it does not decide whether exchange is indicated.

Last reviewed 2026-10-18

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Professional use only

For qualified clinicians. Independently verify inputs, calculations, source guidance, and applicability before any clinical action. This calculator does not replace clinical judgment.

Source: Safer Care Victoria, Clinical Guidance Team (Victoria, Australia). Polycythaemia in neonates. Neonatal eHandbook clinical guidance, first published May 2015, review due May 2018; the page states its review process is paused. Formula: volume of exchange (mL) = blood volume x (observed haematocrit - desired haematocrit) / observed haematocrit. Blood volume is 70-90 mL/kg for term infants and 85-110 mL/kg for preterm infants. The guidance recommends partial exchange transfusion with normal saline as the replacement fluid for symptomatic infants with a venous haematocrit above 70%, aiming to reduce the venous haematocrit below 60%. (2015)

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Clinical inputs

Infant weight (kg)Accepted range: 0.4 to 6
Blood volume per kilogram (mL/kg)Accepted range: 70 to 110
Observed venous haematocrit (%)Accepted range: 60 to 90
Desired haematocrit (%)Accepted range: 45 to 60

Primary source

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