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Gastroenterology · Internal Medicine

Stool Osmotic Gap calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

mOsm/kg

Allowed range: 50–600 mOsm/kg

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mmol/L

Allowed range: 0–200 mmol/L

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mmol/L

Allowed range: 0–200 mmol/L

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Result

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Clinical inputs

  • Measured stool osmolality (mOsm/kg)Accepted range: 50 to 600
  • Stool sodium (mEq/L)Accepted range: 0 to 200
  • Stool potassium (mEq/L)Accepted range: 0 to 200

Primary source

Clinical stool osmotic gap identity used with measured stool osmolality: gap = measured stool osmolarity - 2*(stool Na + stool K). Related osmolality methods literature PMID 1112025 (Dorwart). Scope: osmotic gap >50 mOsm/kg suggests osmotic diarrhea; <50 suggests secretory. (1975)

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