Rheumatology

2016 ACR/EULAR Primary Sjögren Classification calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

Labial salivary gland focus score ≥1 foci/4 mm²Anti-SSA/Ro antibody positiveOcular staining score ≥5 (or van Bijsterveld score ≥4) in at least one eyeSchirmer test ≤5 mm/5 min in at least one eyeUnstimulated whole saliva flow rate ≤0.1 mL/min

Result

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Sjögren classification criteria not met (<4)

Band: Sjögren classification criteria not met (<4)

Interpretation. Sjögren classification criteria not met (<4)

Suggested management. A weighted total below 4 does not classify primary Sjögren's syndrome under the 2016 ACR/EULAR criteria.

2016 ACR/EULAR Primary Sjögren Classification: 0 — Sjögren classification criteria not met (<4). Interpretation: Sjögren classification criteria not met (<4) What to do: A weighted total below 4 does not classify primary Sjögren's syndrome under the 2016 ACR/EULAR criteria. Inputs: Labial salivary gland focus score ≥1 foci/4 mm²: false; Anti-SSA/Ro antibody positive: false; Ocular staining score ≥5 (or van Bijsterveld score ≥4) in at least one eye: false; Schirmer test ≤5 mm/5 min in at least one eye: false; Unstimulated whole saliva flow rate ≤0.1 mL/min: false Source: Shiboski CH et al. 2016 American College of Rheumatology/European League Against Rheumatism classification criteria for primary Sjögren's syndrome. Ann Rheum Dis. DOI: 10.1136/annrheumdis-2016-210571. PMID: 27789466. Scope: among patients with dry eye/mouth symptoms, weighted items (labial biopsy focus score ≥1 = 3, anti-SSA = 3, OSS ≥5 = 1, Schirmer ≤5 mm/5 min = 1, unstimulated saliva ≤0.1 mL/min = 1); total ≥4 classifies primary SS. (2017)

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Clinical inputs

Labial salivary gland focus score ≥1 foci/4 mm²
Anti-SSA/Ro antibody positive
Ocular staining score ≥5 (or van Bijsterveld score ≥4) in at least one eye
Schirmer test ≤5 mm/5 min in at least one eye
Unstimulated whole saliva flow rate ≤0.1 mL/min

Primary source

Shiboski CH et al. 2016 American College of Rheumatology/European League Against Rheumatism classification criteria for primary Sjögren's syndrome. Ann Rheum Dis. DOI: 10.1136/annrheumdis-2016-210571. PMID: 27789466. Scope: among patients with dry eye/mouth symptoms, weighted items (labial biopsy focus score ≥1 = 3, anti-SSA = 3, OSS ≥5 = 1, Schirmer ≤5 mm/5 min = 1, unstimulated saliva ≤0.1 mL/min = 1); total ≥4 classifies primary SS. (2017)

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