Urology · Oncology

PSA Doubling Time calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

Earlier PSA

ng/mL

Allowed range: 0.01–200 ng/mL

Later PSA

ng/mL

Allowed range: 0.01–200 ng/mL

Months between the two PSA measurements

months

Allowed range: 0.5–120 months

Result

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Clinical inputs

Earlier PSA (ng/mL)Accepted range: 0.01 to 200
Later PSA (ng/mL)Accepted range: 0.01 to 200
Months between the two PSA measurementsAccepted range: 0.5 to 120

Primary source

Pound CR et al. Natural history of progression after PSA elevation following radical prostatectomy. JAMA. PMID: 10235151. Doubling time in months is ln(2) × interval / ln(later PSA / earlier PSA). A negative result means the PSA fell. Equal values have no finite doubling time and are reported as 120 months. Pound associated a doubling time under 10 months with metastatic progression. (1999)

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