Allergy · Infectious Disease · Internal Medicine
PEN-FAST Penicillin Allergy Decision Rule calculator
Enter the published formula inputs below to calculate and interpret this score.
Clinical inputs
Result
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0
PEN-FAST 0 — very low risk
Band: PEN-FAST 0 — very low risk
Interpretation. PEN-FAST 0 — very low risk
Suggested management. Very low risk of true penicillin allergy on testing.
PEN-FAST Penicillin Allergy Decision Rule: 0 — PEN-FAST 0 — very low risk. Interpretation: PEN-FAST 0 — very low risk What to do: Very low risk of true penicillin allergy on testing. Inputs: Patient reports a penicillin allergy: false; Allergy ≤5 years ago (+2): false; Anaphylaxis, angioedema, or severe cutaneous adverse reaction (+2): false; Treatment was required for the allergic reaction (+1): false Source: Trubiano JA et al. Development and Validation of a Penicillin Allergy Clinical Decision Rule. JAMA Intern Med. DOI: 10.1001/jamainternmed.2020.0229. PMID: 32176248. Scope: PEN-FAST among patients reporting penicillin allergy — timing ≤5 years (+2), anaphylaxis/angioedema or severe cutaneous adverse reaction (+2), treatment required for the index reaction (+1); total 0–5; 0 very low risk of positive allergy test. (2020)
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Clinical inputs
- Patient reports a penicillin allergy
- Allergy ≤5 years ago (+2)
- Anaphylaxis, angioedema, or severe cutaneous adverse reaction (+2)
- Treatment was required for the allergic reaction (+1)
Primary source
Trubiano JA et al. Development and Validation of a Penicillin Allergy Clinical Decision Rule. JAMA Intern Med. DOI: 10.1001/jamainternmed.2020.0229. PMID: 32176248. Scope: PEN-FAST among patients reporting penicillin allergy — timing ≤5 years (+2), anaphylaxis/angioedema or severe cutaneous adverse reaction (+2), treatment required for the index reaction (+1); total 0–5; 0 very low risk of positive allergy test. (2020)
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