Rheumatology
Leiden Clinical Prediction Rule calculator
Enter the published formula inputs below to calculate and interpret this score.
Clinical inputs
Allowed range: 16–120 years
Each year of age adds 0.02 points.
Allowed range: 0–100 mm
On a 100 mm scale, 0–25 mm scores 0, 26–90 mm scores 1, and above 90 mm scores 2.
Allowed range: 0–44 joints
On the 44-joint count, 0–3 scores 0, 4–10 scores 0.5, and 11 or more scores 1.
Allowed range: 0–44 joints
On the 44-joint count, 0–3 scores 0, 4–10 scores 0.5, and 11 or more scores 1.
Allowed range: 0–50 mg/dL
0–4 mg/L scores 0, 5–50 mg/L scores 0.5, and above 50 mg/L scores 1.5.
Result
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Clinical inputs
- Age (years)Accepted range: 16 to 120
- Sex
- Small joints of the hands or feet
- Symmetric joint distribution
- Limb regions involved
- Morning stiffness (mm)Accepted range: 0 to 100
- Tender joint count (joints)Accepted range: 0 to 44
- Swollen joint count (joints)Accepted range: 0 to 44
- C-reactive protein (mg/L)Accepted range: 0 to 500
- Rheumatoid factor positive
- Anti-CCP antibodies positive
Primary source
van der Helm-van Mil AHM et al. A prediction rule for disease outcome in patients with recent-onset undifferentiated arthritis. Arthritis Rheum. DOI: 10.1002/art.22380. PMID: 17265478. Table 2 and Figure 1. Age in years × 0.02. Female sex 1. Small joints of the hands or feet 0.5. Symmetric distribution 0.5. Upper extremities 1, or upper and lower extremities 1.5. Morning stiffness on a 100 mm scale: 0–25 mm = 0, 26–90 mm = 1, above 90 mm = 2. Tender joints on the 44-joint count: 0–3 = 0, 4–10 = 0.5, 11 or more = 1. Swollen joints use the same bands. CRP: 0–4 mg/L = 0, 5–50 mg/L = 0.5, above 50 mg/L (51 mg/L or higher on the form) = 1.5. Rheumatoid factor 1. Anti-CCP antibodies 2. A score of 6.0 or lower: 91% did not develop rheumatoid arthritis in one year. Above 6.0 and below 8.0: no adequate prediction. 8.0 or higher: progression in 84%. (2007)
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