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Emergency Medicine · Pulmonology · Cardiology

4-Level PE Clinical Probability Score (4PEPS) calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

Age band

Result

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Clinical inputs

  • Age band
  • Chronic respiratory disease (−1)
  • Heart rate <80 beats/min (−1)
  • Chest pain and acute dyspnea (+1)
  • Male sex (+2)
  • Hormonal estrogenic treatment (+2)
  • Personal history of VTE (+2)
  • Syncope (+2)
  • Immobility within the last 4 weeks (+2)
  • Pulse oxygen saturation <95% (+3)
  • Calf pain and/or unilateral lower-limb edema (+3)
  • PE is the most likely diagnosis (+5)

Primary source

Roy PM et al. Derivation and Validation of a 4-Level Clinical Pretest Probability Score for Suspected Pulmonary Embolism to Safely Decrease Imaging Testing. JAMA Cardiol. DOI: 10.1001/jamacardio.2021.0064. PMID: 33656522. Scope: 4PEPS Table 3 points (−2 to +5); bands <0 very low, 0–5 low, 6–12 moderate, ≥13 high. (2021)

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