Primary Care · Pain Medicine

CDC Morphine Milligram Equivalents calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

Opioid

Dose per administration

Allowed range: 0–400 mg

Enter each dose in mg. For a fentanyl patch, enter the strength in mcg/h and enter 1 dose per day.

Doses per day

doses/day

Allowed range: 1–24 doses/day

Result

3 fields remaining

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Professional use only

For qualified clinicians. Independently verify inputs, calculations, source guidance, and applicability before any clinical action. This calculator does not replace clinical judgment.

Source: Dowell D, Ragan KR, Jones CM, Baldwin GT, Chou R. CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States, 2022. MMWR Recomm Rep. PMID: 36327391. Milligram morphine equivalents equal the daily dose times the CDC conversion factor (codeine 0.15, fentanyl patch 2.4 per mcg/hour, hydrocodone 1, hydromorphone 4, morphine 1, oxycodone 1.5, oxymorphone 3, tapentadol 0.4, tramadol 0.1). Methadone uses the dose-banded factors 4, 8, 10, and 12. The guideline advises a pause before increasing the total to 50 MME/day or more. For a fentanyl patch, enter the strength in mcg/hour and 1 dose per day. (2022)

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Clinical inputs

Opioid
Dose per administration (mg)Accepted range: 0 to 400
Doses per day (doses/day)Accepted range: 1 to 24

Primary source

Dowell D, Ragan KR, Jones CM, Baldwin GT, Chou R. CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States, 2022. MMWR Recomm Rep. PMID: 36327391. Milligram morphine equivalents equal the daily dose times the CDC conversion factor (codeine 0.15, fentanyl patch 2.4 per mcg/hour, hydrocodone 1, hydromorphone 4, morphine 1, oxycodone 1.5, oxymorphone 3, tapentadol 0.4, tramadol 0.1). Methadone uses the dose-banded factors 4, 8, 10, and 12. The guideline advises a pause before increasing the total to 50 MME/day or more. For a fentanyl patch, enter the strength in mcg/hour and 1 dose per day. (2022)

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