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Obstetrics

Egg Freezing Live-Birth Counseling calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

Age at egg retrieval

The opened article prints euploid fractions of 0.574 at 35 years or younger, 0.486 at 37 years, and 0.127 at 44 years. Ages 35 years or younger use age 35 years in the blastocyst equation. Other ages are only in Supplementary Table SI, which was not in the opened article.

oocytes

Allowed range: 1–80 oocytes

Quick picks

Count of mature oocytes. The matched examples in the article use 1 group at 35 years and 20 oocytes, and age 37 years with 20 oocytes.

Result

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Clinical inputs

  • Age at egg retrieval
  • Mature oocytesAccepted range: 1 to 80

Primary source

Goldman RH et al. Predicting the likelihood of live birth for elective oocyte cryopreservation: a counseling tool for physicians and patients. Hum Reprod. DOI: 10.1093/humrep/dex008. PMID: 28166330. Equation 1: probability that one mature oocyte becomes a blastocyst = survival × exp(2.8043 − 0.1112 × age). Survival is 0.95 below 36 years and 0.85 at 36 years or older. The article groups every patient 35.0 years or younger together; using age 35 years in Equation 1 reproduces the printed 90% chance of at least one live birth from 20 mature oocytes. Printed euploid fractions in the article text are 0.574 at 35 years or younger, 0.486 at 37 years, and 0.127 at 44 years. Equation 2 for at least one live birth is 1 − (1 − 0.6 × euploid fraction × blastocyst probability)^oocyte count. The 0.6 is the live-birth rate per transferred euploid blastocyst. At least two and at least three use that same per-oocyte probability under the article's statement that each oocyte's outcome is statistically independent. Age 34 years with 20 oocytes prints 66% and 38% for at least two and three. Age 37 years with 20 oocytes prints 75%, 39%, and 15%. Other integer ages are listed only in Supplementary Table SI, which was not in the opened article, so they are not offered. (2017)

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