Internal Medicine · Emergency Medicine

Worthley Calculated Serum Osmolality calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

Serum sodium (mmol/L)

Serum glucose (mg/dL)

Blood urea nitrogen (mg/dL)

Result

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Formula inputs

Serum sodium (mmol/L)Accepted range: 50 to 250
Serum glucose (mg/dL)Accepted range: 0 to 3000
Blood urea nitrogen (mg/dL)Accepted range: 0 to 500

Primary source

Worthley LIG et al. For Calculating Osmolality, the Simplest Formula is the Best. Anaesth Intensive Care. DOI: 10.1177/0310057X8701500214. PMID: 3605570. Scope: calculated serum osmolality in conventional US laboratory units; not a substitute for measured osmolality when an osmolar gap is clinically relevant. (1987)

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