Internal Medicine · Emergency Medicine · Nephrology

Serum Anion Gap calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

Serum sodium

mmol/L

Allowed range: 100–180 mmol/L

Serum chloride

mmol/L

Allowed range: 70–140 mmol/L

Serum bicarbonate

mmol/L

Allowed range: 5–45 mmol/L

Result

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Clinical inputs

Serum sodium (mmol/L)Accepted range: 100 to 180
Serum chloride (mmol/L)Accepted range: 70 to 140
Serum bicarbonate (mmol/L)Accepted range: 5 to 45

Primary source

Emmett M, Narins RG. Clinical use of the anion gap. Medicine (Baltimore). DOI: 10.1097/00005792-197705000-00001. PMID: 850698. Scope: standard serum anion gap = sodium − (chloride + bicarbonate) in mEq/L or mmol/L. (1977)

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