Nephrology · Internal Medicine

Sodium Chloride Deficit (Hyponatremia) calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

Weight (kg)

Allowed range: 4.41–440.92 lb

Measured sodium (mmol/L)

mmol/L

Allowed range: 100–140 mmol/L

Target sodium (mmol/L)

mmol/L

Allowed range: 120–145 mmol/L

Patient group (total body water fraction)

Result

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Professional use only

For qualified clinicians. Independently verify inputs, calculations, source guidance, and applicability before any clinical action. This calculator does not replace clinical judgment.

Source: Sodium deficit (mmol) = total body water × (target Na − measured Na), with total body water = fraction × weight (MSD Manual Professional, Sodium Deficit in Hyponatremia calculator). Water fractions from Adrogué HJ, Madias NE. Hyponatremia. N Engl J Med. 2000;342(21):1581-1589 (PMID 10824078, DOI 10.1056/NEJM200005253422107): children 0.6, adult men 0.6, adult women 0.5, elderly men 0.5, elderly women 0.45. MSD Manual's hyponatremia correction calculator (citing Adrogué & Madias) states that serum sodium should generally be corrected at a rate that does not exceed 8 mEq/L per day. (2000)

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Clinical inputs

Weight (kg)Accepted range: 2 to 200
Measured sodium (mmol/L)Accepted range: 100 to 140
Target sodium (mmol/L)Accepted range: 120 to 145
Patient group (total body water fraction)

Primary source

Sodium deficit (mmol) = total body water × (target Na − measured Na), with total body water = fraction × weight (MSD Manual Professional, Sodium Deficit in Hyponatremia calculator). Water fractions from Adrogué HJ, Madias NE. Hyponatremia. N Engl J Med. 2000;342(21):1581-1589 (PMID 10824078, DOI 10.1056/NEJM200005253422107): children 0.6, adult men 0.6, adult women 0.5, elderly men 0.5, elderly women 0.45. MSD Manual's hyponatremia correction calculator (citing Adrogué & Madias) states that serum sodium should generally be corrected at a rate that does not exceed 8 mEq/L per day. (2000)

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