ICU and Critical Care · Pulmonology

ROX Index for High-Flow Nasal Cannula at 2, 6, and 12 Hours calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

Time after starting high-flow nasal cannula

Use in adults with pneumonia and acute hypoxemic respiratory failure receiving high-flow nasal cannula. Calculate from values measured at 2, 6, or 12 hours after high-flow initiation.

Oxygen saturation (SpO₂)

Allowed range: 1–100 %

Inspired oxygen fraction (FiO₂ as 0.21–1.00)

fraction

Allowed range: 0.21–1 fraction

Respiratory rate (breaths/min)

/min

Allowed range: 1–100 /min

Result

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Clinical inputs

Time after starting high-flow nasal cannula
Oxygen saturation (SpO₂) (%)Accepted range: 1 to 100
Inspired oxygen fraction (FiO₂ as 0.21–1.00)Accepted range: 0.21 to 1
Respiratory rate (breaths/min)Accepted range: 1 to 100

Primary source

Roca O et al. An Index Combining Respiratory Rate and Oxygenation to Predict Outcome of Nasal High-Flow Therapy. Am J Respir Crit Care Med. DOI: 10.1164/rccm.201803-0589OC. PMID: 30576221 (2019)

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