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Internal Medicine · Emergency Medicine · Toxicology

Serum Osmolal Gap calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

mOsm/kg

Allowed range: 250–400 mOsm/kg

Quick picks
mOsm/kg

Allowed range: 250–400 mOsm/kg

Quick picks

Result

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Clinical inputs

  • Measured serum osmolality (mOsm/kg)Accepted range: 250 to 400
  • Calculated serum osmolality (mOsm/kg)Accepted range: 250 to 400

Primary source

Dorwart WV, Chalmers L. Comparison of methods for calculating serum osmolality from chemical concentrations. Am J Clin Pathol. DOI: 10.1093/ajcp/67.5.484. PMID: 859258. Scope: osmolal gap = measured serum osmolality − calculated serum osmolality (mOsm/kg); an elevated gap suggests unmeasured osmoles. (1977)

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