Internal Medicine · Emergency Medicine · Toxicology
Serum Osmolal Gap calculator
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Formula inputs
- Measured serum osmolality (mOsm/kg)Accepted range: 250 to 400
- Calculated serum osmolality (mOsm/kg)Accepted range: 250 to 400
Primary source
Dorwart WV, Chalmers L. Comparison of methods for calculating serum osmolality from chemical concentrations. Am J Clin Pathol. DOI: 10.1093/ajcp/67.5.484. PMID: 859258. Scope: osmolal gap = measured serum osmolality − calculated serum osmolality (mOsm/kg); an elevated gap suggests unmeasured osmoles. (1977)
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