Haematology · Internal Medicine
HERDOO2 Rule (Unprovoked VTE in Women) calculator
Enter the published formula inputs below to calculate and interpret this score.
Clinical inputs
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0
HERDOO2 low risk (0–1 criteria)
Band: HERDOO2 low risk (0–1 criteria)
Interpretation. HERDOO2 low risk (0–1 criteria)
Suggested management. Women with 0–1 HERDOO2 criteria are low recurrence risk and may discontinue anticoagulation after short-term treatment (Rodger BMJ 2017). Men continue anticoagulation.
HERDOO2 Rule (Unprovoked VTE in Women): 0 — HERDOO2 low risk (0–1 criteria). Interpretation: HERDOO2 low risk (0–1 criteria) What to do: Women with 0–1 HERDOO2 criteria are low recurrence risk and may discontinue anticoagulation after short-term treatment (Rodger BMJ 2017). Men continue anticoagulation. Inputs: Age ≥65 years: false; Obesity (BMI ≥30 kg/m²): false; Hyperpigmentation, edema, or redness in either leg: false; D-dimer ≥250 μg/L while anticoagulated: false Source: Rodger MA et al. Validating the HERDOO2 rule to guide treatment duration for women with unprovoked venous thrombosis: multinational prospective cohort management study. BMJ. 2017;356:j1065. DOI: 10.1136/bmj.j1065. PMID: 28314711. PMC: PMC6287588. Criteria: Hyperpigmentation/Edema/Redness in either leg; D-dimer ≥250 μg/L on anticoagulants; Obesity BMI ≥30; Older age ≥65 years. Low risk = 0 or 1 criterion; high risk = ≥2. (2017)
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Clinical inputs
- Age ≥65 years
- Obesity (BMI ≥30 kg/m²)
- Hyperpigmentation, edema, or redness in either leg
- D-dimer ≥250 μg/L while anticoagulated
Primary source
Rodger MA et al. Validating the HERDOO2 rule to guide treatment duration for women with unprovoked venous thrombosis: multinational prospective cohort management study. BMJ. 2017;356:j1065. DOI: 10.1136/bmj.j1065. PMID: 28314711. PMC: PMC6287588. Criteria: Hyperpigmentation/Edema/Redness in either leg; D-dimer ≥250 μg/L on anticoagulants; Obesity BMI ≥30; Older age ≥65 years. Low risk = 0 or 1 criterion; high risk = ≥2. (2017)
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