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Cardiology · Internal Medicine

Framingham General CVD Risk 2008 (D'Agostino, Sex-Specific) calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

framingham sex
years

Allowed range: 30–74 years

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mg/dL

Allowed range: 100–400 mg/dL

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mg/dL

Allowed range: 10–150 mg/dL

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mmHg

Allowed range: 80–300 mmHg

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framingham blood pressure treated
framingham current smoker
Diabetes

Result

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Clinical inputs

  • framingham sex
  • framingham age yearsAccepted range: 30 to 74
  • framingham total cholesterol mg dl (mg/dL)Accepted range: 100 to 400
  • framingham hdl cholesterol mg dl (mg/dL)Accepted range: 10 to 150
  • framingham systolic bp mmhgAccepted range: 80 to 300
  • framingham blood pressure treated
  • framingham current smoker
  • Diabetes

Primary source

D'Agostino RB Sr et al. General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation. DOI: 10.1161/CIRCULATIONAHA.107.699579. PMID: 18212285. Scope: sex-specific Cox models (ages 30–74, no baseline CVD) predicting 10-year risk of a first general CVD event (coronary heart disease, stroke, peripheral artery disease, or heart failure) — not isolated 'hard CHD'. Risk = 1 − S0(10)^exp(Σ(β·X) − mean). Men: S0=0.88936, mean=23.9802, β: ln(age) 3.06117, ln(TC) 1.1237, ln(HDL) −0.93263, ln(SBP untreated) 1.93303 / treated 1.99881, smoker 0.65451, diabetes 0.57367. Women: S0=0.95012, mean=26.1931, β: ln(age) 2.32888, ln(TC) 1.20904, ln(HDL) −0.70833, ln(SBP untreated) 2.76157 / treated 2.82263, smoker 0.52873, diabetes 0.69154. (2008)

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