Infectious Disease · ICU and Critical Care
4C Mortality Score (COVID-19) calculator
Enter the published formula inputs below to calculate and interpret this score.
Clinical inputs
Allowed range: 18–120 years
Years at hospital assessment. Table 2: <50 = 0; 50–59 = +2; 60–69 = +4; 70–79 = +6; ≥80 = +7.
Allowed range: 0–20 count
Charlson comorbidity count (plus clinician-defined obesity). Table 2: 0 = 0; 1 = +1; ≥2 = +2.
Allowed range: 5–60 breaths/min
Allowed range: 50–100 %
SpO₂ on room air (%). Table 2: ≥92% = 0; <92% = +2.
Allowed range: 3–360.36 mg/dL
Allowed range: 0–50 mg/dL
Result
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Clinical inputs
- Age (years)Accepted range: 18 to 120
- Sex at birth
- Number of comorbidities (count)Accepted range: 0 to 20
- Respiratory rate (breaths/min)Accepted range: 5 to 60
- Peripheral oxygen saturation on room air (%)Accepted range: 50 to 100
- Glasgow Coma Scale
- Urea (mmol/L)Accepted range: 0.5 to 60
- C-reactive protein (mg/L)Accepted range: 0 to 500
Primary source
Knight SR et al. Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score. BMJ. DOI: 10.1136/bmj.m3339. PMID: 33332546. Scope: 4C Mortality Score Table 2 points (age, sex, comorbidity count, RR, SpO2 on room air, GCS, urea mmol/L, CRP mg/L) and Table 5 risk groups for in-hospital mortality. (2020)
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