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Endocrinology · Emergency Medicine

Effective Serum Osmolality (Tonicity) calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

Result

Complete all required inputs to calculate the score.

Formula inputs

  • Measured serum sodium (mmol/L)Accepted range: 50 to 250
  • Serum glucose (mg/dL)Accepted range: 0 to 3000

Primary source

Kitabchi AE et al. Hyperglycemic crises in adult patients with diabetes. Diabetes Care. DOI: 10.2337/dc09-9032. PMID: 19564476. Scope: effective serum osmolality in adult hyperglycemic crises, excluding BUN because urea is an ineffective osmole. (2009)

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