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Endocrinology · Emergency Medicine

Effective Serum Osmolality (Tonicity) calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

mmol/L

Allowed range: 50–250 mmol/L

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mg/dL

Allowed range: 0–3000 mg/dL

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Result

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Clinical inputs

  • Measured serum sodium (mmol/L)Accepted range: 50 to 250
  • Serum glucose (mg/dL)Accepted range: 0 to 3000

Primary source

Kitabchi AE et al. Hyperglycemic crises in adult patients with diabetes. Diabetes Care. DOI: 10.2337/dc09-9032. PMID: 19564476. Scope: effective serum osmolality in adult hyperglycemic crises, excluding BUN because urea is an ineffective osmole. (2009)

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