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Haematology

DIPSS Plus calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

DIPSS risk category

Enter the already determined DIPSS risk category. DIPSS Plus transforms low, intermediate-1, intermediate-2, and high DIPSS categories to 0, 1, 2, and 3 points; it does not rescore the five raw DIPSS variables.

Unfavorable karyotype: complex or one or two abnormalities including (+8), −7/7q−, i(17q), inv(3), −5/5q−, 12p−, or 11q23 rearrangement
Platelet count <100 ×10⁹/L
Red-cell transfusion need

Result

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Clinical inputs

  • DIPSS risk category
  • Unfavorable karyotype: complex or one or two abnormalities including (+8), −7/7q−, i(17q), inv(3), −5/5q−, 12p−, or 11q23 rearrangement
  • Platelet count <100 ×10⁹/L
  • Red-cell transfusion need

Primary source

Gangat N et al. DIPSS plus: a refined Dynamic International Prognostic Scoring System for primary myelofibrosis that incorporates prognostic information from karyotype, platelet count, and transfusion status. J Clin Oncol. DOI: 10.1200/JCO.2010.32.2446. PMID: 21149668 (2011)

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