Internal Medicine · Emergency Medicine · Nephrology
Delta Gap Ratio (ΔAG/ΔHCO₃⁻) calculator
Enter the published formula inputs below to calculate and interpret this score.
Clinical inputs
Allowed range: 100–180 mmol/L
Allowed range: 70–140 mmol/L
Allowed range: 0–50 mmol/L
Allowed range: 6–16 mmol/L
Reference anion gap used for delta calculations; 12 mEq/L is a conventional adult reference value.
Allowed range: 20–28 mmol/L
Reference serum bicarbonate used for delta bicarbonate; 24 mmol/L is a common laboratory reference midpoint.
Result
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Clinical inputs
- Serum sodium (mmol/L)Accepted range: 100 to 180
- Serum chloride (mmol/L)Accepted range: 70 to 140
- Serum bicarbonate (mmol/L)Accepted range: 0 to 50
- Reference anion gap (mEq/L)Accepted range: 6 to 16
- Reference serum bicarbonate (mmol/L)Accepted range: 20 to 28
Primary source
Wrenn K. The delta (delta) gap: an approach to mixed acid-base disorders. Ann Emerg Med. 1990;19:1310-1313. DOI: 10.1016/S0196-0644(05)82292-9. PMID: 2240729. Scope: delta gap ratio = Δanion gap / Δbicarbonate, where Δanion gap = measured anion gap − reference anion gap and Δbicarbonate = reference bicarbonate − measured bicarbonate. (1990)
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