Use PaO₂ when FiO₂ <0.50; use alveolar–arterial oxygen difference when FiO₂ ≥0.50.
Use arterial pH when available. The labels also show the published serum bicarbonate substitute.
Double the acute-physiology creatinine points when acute renal failure is present.
APACHE II neurologic points equal 15 minus the measured GCS; assess before sedation when possible.
Applies to severe organ-system insufficiency or immunocompromise documented before this admission.