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Pulmonology · ICU and Critical Care

Alveolar–Arterial Oxygen Gradient calculator

Enter the published formula inputs below to calculate and interpret this score.

Clinical inputs

fraction

Allowed range: 0.21–1 fraction

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mmHg

Allowed range: 10–150 mmHg

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mmHg

Allowed range: 20–600 mmHg

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mmHg

Allowed range: 500–780 mmHg

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Use local barometric pressure (760 mmHg at sea level).

mmHg

Allowed range: 40–50 mmHg

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ratio

Allowed range: 0.7–1 ratio

Respiratory quotient; 0.8 is standard unless measured.

Result

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Clinical inputs

  • aagradient fio2 fractionAccepted range: 0.21 to 1
  • aagradient paco2 mmhgAccepted range: 10 to 150
  • aagradient pao2 mmhgAccepted range: 20 to 600
  • aagradient barometric pressure mmhgAccepted range: 500 to 780
  • aagradient water vapor pressure mmhgAccepted range: 40 to 50
  • aagradient respiratory quotient (ratio)Accepted range: 0.7 to 1

Primary source

Alveolar gas equation as used in arterial blood gas interpretation. DOI: 10.1164/ajrccm.158.1.9711041. PMID: 9655694. Scope: calculates P(A–a)O₂ as (PB − PH₂O) × FiO₂ − PaCO₂/RQ − PaO₂ for adult arterial blood gas assessment. (1998)

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